Article
Integrated copy number and expression analysis identifies profiles of whole-arm chromosomal alterations and subgroups with favorable outcome in ovarian clear cell carcinomas.
PloS one - 1 Jan 2015
Uehara Yuriko, Oda Katsutoshi, Ikeda Yuji, Koso Takahiro, Tsuji Shingo, Yamamoto Shogo, Asada Kayo, Sone Kenbun, Kurikawa Reiko, Makii Chinami, Hagiwara Otoe, Tanikawa Michihiro, Maeda Daichi, Hasegawa Kosei, Nakagawa Shunsuke, Wada-Hiraike Osamu, Kawana Kei, Fukayama Masashi, Fujiwara Keiichi, Yano Tetsu, Osuga Yutaka, Fujii Tomoyuki, Aburatani Hiroyuki
Abstract excerpt
Ovarian clear cell carcinoma (CCC) is generally associated with chemoresistance and poor clinical outcome, even with early diagnosis; whereas high-grade serous carcinomas (SCs) and endometrioid carcinomas (ECs) are commonly chemosensitive at advanced stages. Although an integrated genomic analysis of SC has been performed, conclusive views on copy number and expression profiles for CCC are still limited. In this...
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