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Genomic Analysis Reveals the Molecular Heterogeneity of Ovarian Clear Cell Carcinomas

15 Mar 2011

Abstract excerpt

PURPOSE: Ovarian clear cell carcinomas (OCCC) are a drug-resistant and aggressive type of epithelial ovarian cancer. We analyzed the molecular genetic profiles of OCCCs to determine whether distinct genomic subgroups of OCCCs exist. EXPERIMENTAL DESIGN: Fifty pure primary OCCCs were subjected to high-resolution microarray-based comparative genomic hybridization (aCGH). Unsupervised hierarchical clustering using...

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Share to Chromatin Remodeling and Cancer
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PMID: 21411445
DOI: 10.1158/1078-0432.ccr-10-1688

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