Article
Analysis of gene expression signatures identifies prognostic and functionally distinct ovarian clear cell carcinoma subtypes.
EBioMedicine - 1 Dec 2019
Tan Tuan Zea, Ye Jieru, Yee Chung Vin, Lim Diana, Ngoi Natalie Yan Li, Tan David Shao Peng, Huang Ruby Yun-Ju
Abstract excerpt
BACKGROUND: Ovarian clear cell carcinoma (OCCC) is a histological subtype of epithelial ovarian cancer (EOC) with distinct pathological, biological, and molecular features. OCCCs are more resistant to conventional treatment regimen of EOC and have the worst stage-adjusted prognosis amongst EOC subtypes. As the OCCC incidence rate in Asian populations has significantly increased in recent decades, it is critical...
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