Article
NFE2L2 Gene Variants and Arsenic Susceptibility: A Lymphoblastoid Model.
Journal of toxicology and environmental health. Part A - 1 Jan 2015
Morales-Marin Mirna E, Cordova Emilio J, Centeno Federico, Martínez-Hernández Angélica, Méndez-García Angélica, Molina Bertha, Frías Sara, Orozco Lorena
Abstract excerpt
Arsenic (As) exposure is a major risk for several types of cancer and metabolic diseases such as diabetes. The transcription factor nuclear factor erythroid 2-related factor (Nrf2) is a key mediator in the cellular defense against As-induced adverse effects. The -653G/A and -617C/A gene variants...
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