Article
Nuclear factor erythroid 2-related factor gene variants and susceptibility of arsenic-related skin lesions.
Human & experimental toxicology - 1 Jun 2014
Cordova E J, Valenzuela O L, Sánchez-Peña L C, Escamilla-Guerrero G, Hernández-Zavala A, Orozco L, Del Razo L M
Abstract excerpt
Inorganic arsenic (iAs) is an important pollutant associated with various chronic-degenerative diseases. The cytoprotective protein nuclear factor erythroid 2-related factor (NRF2) has been proposed as an important responsive mechanism against iAs exposure. The aim of this study was to determine whether the risk of skin lesions in people exposed to iAs-contaminated water could be modified by the presence of...
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