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Article

Identification of polymorphisms in the promoter region of the human NRF2 gene.

Biochemical and biophysical research communications - 13 Aug 2004

Yamamoto Tae, Yoh Keigyou, Kobayashi Akira, Ishii Yukio, Kure Shigeo, Koyama Akio, Sakamoto Tohru, Sekizawa Kiyohisa, Motohashi Hozumi, Yamamoto Masayuki

Abstract excerpt

Transcription factor Nrf2 regulates the basal and inducible expression of detoxifying and antioxidant genes. Recent studies using nrf2-null mice suggest that Nrf2 dysfunction might be involved in the pathogenesis of human diseases. To gain insight into the relationship between impairment in the NRF2 gene and human diseases, we attempted to identify polymorphisms in the human NRF2 gene. We determined the structure...

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Identifiers

PMID: 15358217
DOI: 10.1016/j.bbrc.2004.06.112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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