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Article

Genetics of kidney failure and the evolving story of APOL1.

The Journal of clinical investigation - 1 Sept 2011

Friedman David J, Pollak Martin R

Abstract excerpt

Chronic kidney disease (CKD) results from a wide array of processes that impair the kidney's ability to perform its major functions. As many as 20 million Americans suffer from CKD and nearly a half million from end-stage renal disease, but there are also examples of centenarians with adequate renal function. Family-based and genome-wide studies suggest that genetic differences substantially influence an...

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Source

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Identifiers

PMID: 21881214
DOI: 10.1172/JCI46263
PMCID: PMC3163957

Genes

APOL1

Provenance

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