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Article

miR-153 inhibits epithelial-to-mesenchymal transition in hepatocellular carcinoma by targeting Snail

28 May 2015

Abstract excerpt

Epithelial-to-mesenchymal transition (EMT) has been implicated as a dynamic cellular process in embryonic development and invasion of human cancers. Snail1 is a critical convergence hub in EMT regulation which transcriptionally represses E-cadherin expression. Currently, published data indicate that upregulation of Snail is mainly due to transcriptional activation and regulation of protein stability and cellular...

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Identifiers

PMID: 26035427
DOI: 10.3892/or.2015.4008

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