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Article

miR-181b-3p promotes epithelial-mesenchymal transition in breast cancer cells through Snail stabilization by directly targeting YWHAG.

Biochimica et biophysica acta - 1 Jul 2016

Yoo Je-Ok, Kwak Seo-Young, An Hyun-Ju, Bae In-Hwa, Park Myung-Jin, Han Young-Hoon

Abstract excerpt

Epithelial-mesenchymal transition (EMT) is essential for increased invasion and metastasis during cancer progression. Among the candidate EMT-regulating microRNAs that we previously identified, miR-181b-3p was found to induce EMT in MCF7 breast cancer cells, as indicated by an EMT-characteristic morphological change, increased invasiveness, and altered expression of an EMT marker. Transfection with a miR-181b-3p...

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Source

Identifiers

PMID: 27102539
DOI: 10.1016/j.bbamcr.2016.04.016

Genes

YWHAG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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