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Article

Action and function of Wnt/β-catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma.

Journal of gastroenterology - 1 Apr 2017

Wang Wenhui, Pan Qiuwei, Fuhler Gwenny M, Smits Ron, Peppelenbosch Maikel P

Abstract excerpt

Hepatitis C virus (HCV) infection is one of the leading causes of hepatocellular carcinoma (HCC) worldwide but the mechanistic basis as to how chronic HCV infection furthers the HCC process remains only poorly understood. Accumulating evidence indicates that HCV core and nonstructural proteins provoke activation of the Wnt/β-catenin signaling pathway, and the evidence supporting a role of Wnt/β-catenin signaling...

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Source

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Identifiers

PMID: 28035485
DOI: 10.1007/s00535-016-1299-5
PMCID: PMC5357489

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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