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Article

A rat model for LGI1-related epilepsies

15 May 2012

Abstract excerpt

Mutations of the leucine-rich glioma-inactivated 1 (LGI1) gene cause an autosomal dominant partial epilepsy with auditory features also known as autosomal-dominant lateral temporal lobe epilepsy. LGI1 is also the main antigen present in sera and cerebrospinal fluids of patients with limbic encephalitis and seizures, highlighting its importance in a spectrum of epileptic disorders. LGI1 encodes a neuronal secreted...

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PMID: 22589250
DOI: 10.1093/hmg/dds184

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A rat model for LGI1-related epilepsiesPMID 22589250Read ↗

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