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Article

Mutations in LGI1 cause autosomal-dominant partial epilepsy with auditory features.

Nature genetics - 1 Mar 2002

Kalachikov Sergey, Evgrafov Oleg, Ross Barbara, Winawer Melodie, Barker-Cummings Christie, Martinelli Boneschi Filippo, Choi Chang, Morozov Pavel, Das Kamna, Teplitskaya Elita, Yu Andrew, Cayanis Eftihia, Penchaszadeh Graciela, Kottmann Andreas H, Pedley Timothy A, Hauser W Allen, Ottman Ruth, Gilliam T Conrad

Abstract excerpt

The epilepsies are a common, clinically heterogeneous group of disorders defined by recurrent unprovoked seizures. Here we describe identification of the causative gene in autosomal-dominant partial epilepsy with auditory features (ADPEAF, MIM 600512), a rare form of idiopathic lateral temporal lobe epilepsy characterized by partial seizures with auditory disturbances. We constructed a complete, 4.2-Mb physical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11810107
DOI: 10.1038/ng832
PMCID: PMC2606053

Genes

LGI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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