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Article

[Role of transcription factors in transdifferentiation of the gastric mucosa].

TSitologiia i genetika - 1 Jan 2000

Vernygorodskyi S V, Degtiariova L V, Iatsyna O I, Blume Ya B, Yemets A I

Abstract excerpt

The analysis of intestinal differentiation transcription factor CDX2 in the gastric mucosa biopsies has been carried out. It was established that CDX2 by itself promoter activation pathway can obtain intestinal phenotype for gastric mucosa cells. The loss of CDX2 expression in the nuclei of metaplastic epithelium may serve as a predictor of gastric mucosa malignization.

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Source

Identifiers

PMID: 26030973

Genes

CDX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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