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Article

Expression of the intestine-specific transcription factors, Cdx1 and Cdx2, correlates shift to an intestinal phenotype in gastric cancer cells.

Journal of cancer research and clinical oncology - 1 Jan 2004

Mizoshita Tsutomu, Inada Ken-ichi, Tsukamoto Tetsuya, Nozaki Koji, Joh Takashi, Itoh Makoto, Yamamura Yoshitaka, Ushijima Toshikazu, Nakamura Shigeo, Tatematsu Masae

Abstract excerpt

PURPOSE: It is well known that gastric cancers (GCs) at early stages, independent of the histological type, mainly consist of gastric phenotype malignant cells, while those at advanced stage tend to have a more intestinal phenotype with progression. However, the connection between this shift and expression of homeobox genes, which are important factors to maintain tissue character, has remained unclear. We...

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Identifiers

PMID: 14615935
DOI: 10.1007/s00432-003-0503-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Expression of the intestine-specific transcription factors, Cdx1 and Cdx2, correlates shift to an intestinal phenotype in gastric cancer cells.PMID 14615935Read ↗

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