Article
Gene and stress history interplay in emergence of PTSD-like features.
Behavioural brain research - 1 Oct 2015
Chakraborty Nabarun, Meyerhoff James, Gautam Aarti, Muhie Seid, Jibitu Meskerem, De Lima Thereza C M, Hammamieh Rasha, Jett Marti
Abstract excerpt
Systematically distinguishing genetic liability from other contributing factors is critical for designing a preventive strategy for post-traumatic stress disorder (PTSD). To address this issue, we investigated a murine model exposing C57BL/6j, DBA/2j and BALB/cj mice to repeated stress via exposure to conspecific aggressors (Agg-E). Naïve mice from each strain were subjected to the proximity of aggressor (Agg)...
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