Article
Genome to Phenome: A Systems Biology Approach to PTSD Using an Animal Model.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Chakraborty Nabarun, Meyerhoff James, Jett Marti, Hammamieh Rasha
Abstract excerpt
Post-traumatic stress disorder (PTSD) is a debilitating illness that imposes significant emotional and financial burdens on military families. The understanding of PTSD etiology remains elusive; nonetheless, it is clear that PTSD is manifested by a cluster of symptoms including hyperarousal, reexperiencing of traumatic events, and avoidance of trauma reminders. With these characteristics in mind, several rodent...
Topics
- Animals
- Biomarkers
- Disease Models, Animal
- Genome-Wide Association Study
- Genomics
- Genotype
- Humans
- Magnetic Resonance Imaging
- Phenotype
- Stress Disorders, Post-Traumatic
- Systems Biology
