Article
Post-traumatic stress behavioural responses in inbred mouse strains: can genetic predisposition explain phenotypic vulnerability?
The international journal of neuropsychopharmacology - 1 May 2008
Cohen Hagit, Geva Amir B, Matar Michael A, Zohar Joseph, Kaplan Zeev
Abstract excerpt
Clinical studies of twin pairs and families of post-traumatic stress disorder (PTSD) patients raise questions as to possible genetic predisposition to PTSD. Studies using isogenic animal populations exposed to a stress paradigm could elucidate the relative contributions of genotype and environment to endophenotypic expression. The prevalence of individuals displaying severely compromised behavioural responses to...
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