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Article

Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells

25 May 2015

Abstract excerpt

BACKGROUND & AIMS: The differentiation of stem cells to hepatocyte-like cells (HLC) offers the perspective of unlimited supply of human hepatocytes. However, the degree of differentiation of HLC remains controversial. To obtain an unbiased characterization, we performed a transcriptomic study with HLC derived from human embryonic and induced stem cells (ESC, hiPSC) from three different laboratories. METHODS:...

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PMID: 26022688
DOI: 10.1016/j.jhep.2015.05.013

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