Article

Mapping human liver development using single-cell transcriptomics to reveal pathways directing stem cell fates

2020-01-01

Abstract excerpt

The liver is an organ with a diversity of essential functions including xenobiotic removal, bile acid production, storage of iron and vitamins, and metabolism of glucose and fatty acids. Hepatocytes, comprising the liver parenchyma, fulfil these functions and form an extensive network with non-parenchymal cholangiocytes, endothelial cells, Kupffer cells, and hepatic stellate cells. Disorders affecting hepatocytes...

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Literature Corpus work: 17e50cd9-9f97-5e5c-9e96-fe6785fb6fd8
DOI: 10.17863/cam.66577

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