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Article

Discrete associations of the GCKR variant with metabolic risk in a Chinese population: longitudinal change analysis.

Diabetologia - 1 Feb 2016

Xu Min, Lv Xiaofei, Xie Lan, Huang Xiaolin, Huang Ya, Chen Ying, Peng Kui, Wang Po, Wang Weiqing, Qi Lu, Bi Yufang, Sun Yimin, Ning Guang

Abstract excerpt

AIMS/HYPOTHESIS: Glucokinase regulatory protein gene (GCKR) variant rs780092 is a novel genetic variant associated with serum triacylglycerol (TG) identified in a genome-wide association study in East Asians. We aimed to investigate associations of rs780092 with incident type 2 diabetes and dyslipidaemia, and the longitudinal changes in glucose and lipid levels. METHODS: A community-based prospective cohort study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adaptor Proteins, Signal Transducing
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Source

Identifiers

PMID: 26515422
DOI: 10.1007/s00125-015-3788-0

Genes

GCKR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Discrete associations of the GCKR variant with metabolic risk in a Chinese population: longitudinal change analysis.PMID 26515422Read ↗

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Associations of common polymorphisms in GCKR with type 2 diabetes and related traits in a Han Chinese population: a case-control study.Semantic proximity Read ↗

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes.Semantic proximity Read ↗

Association of GCKR rs780094, alone or in combination with GCK rs1799884, with type 2 diabetes and related traits in a Han Chinese population.Semantic proximity Read ↗

Association of rs780094 in GCKR with metabolic traits and incident diabetes and cardiovascular disease: the ARIC Study.Semantic proximity Read ↗

GCKR Common Functional Polymorphisms are Associated with Metabolic Syndrome and its Components: A 10-Year Retrospective Cohort Study in Iranian AdultsSemantic proximity Read ↗

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The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels and lower HOMA-IR in Japanese population.Semantic proximity Read ↗

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