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Article

Polygenic risk for triglyceride levels in the presence of a high impact rare variant

2023-09-19

Abstract excerpt

<h4>Background: </h4> Elevated triglyceride (TG) levels are a heritable and modifiable risk factor for cardiovascular disease and have well-established associations with common genetic variation captured in a polygenic risk score (PRS). In young adulthood, the 22q11.2 microdeletion conveys a 2-fold increased risk for mild-moderate hypertriglyceridemia. This study aimed to assess the role of the TG-PRS in individua...

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Identifiers and source

Literature Corpus work
6c58cb17-f5ba-5957-84be-1c074c88b915
DOI
10.21203/rs.3.rs-2849516/v1
Open publication

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