Article
HLA Typing for the Next Generation.
PloS one - 1 Jan 2015
Mayor Neema P, Robinson James, McWhinnie Alasdair J M, Ranade Swati, Eng Kevin, Midwinter William, Bultitude Will P, Chin Chen-Shan, Bowman Brett, Marks Patrick, Braund Henny, Madrigal J Alejandro, Latham Katy, Marsh Steven G E
Abstract excerpt
Allele-level resolution data at primary HLA typing is the ideal for most histocompatibility testing laboratories. Many high-throughput molecular HLA typing approaches are unable to determine the phase of observed DNA sequence polymorphisms, leading to ambiguous results. The use of higher resolution methods is often restricted due to cost and time limitations. Here we report on the feasibility of using Pacific...
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