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Article

High-resolution, high-throughput HLA genotyping by next-generation sequencing.

Tissue antigens - 1 Nov 2009

Bentley G, Higuchi R, Hoglund B, Goodridge D, Sayer D, Trachtenberg E A, Erlich H A

Abstract excerpt

The human leukocyte antigen (HLA) class I and class II loci are the most polymorphic genes in the human genome. Hematopoietic stem cell transplantation requires allele-level HLA typing at multiple loci to select the best matched unrelated donors for recipient patients. In current methods for HLA typing, both alleles of a heterozygote are amplified and typed or sequenced simultaneously, often making it difficult...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 19845894
DOI: 10.1111/j.1399-0039.2009.01345.x
PMCID: PMC4205125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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