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Article

Association between XRCC3 Thr241Met polymorphism and laryngeal cancer susceptibility in Turkish population.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Dec 2015

Mutlu Pelin, Mutlu Murad, Yalçın Serap, Yaylacı Atılay, Ünsoy Gözde, Saylam Güleser, Akın İstemihan, Gündüz Ufuk, Korkmaz Hakan

Abstract excerpt

DNA repair systems are essential for normal cell function. Genetic alterations in the DNA repair genes such as X-ray repair cross-complementing group 3 (XRCC3), can cause a change in protein activity which results in cancer susceptibility. The aim of this study was to investigate the association of XRCC3 Thr241Met single nucleotide polymorphism (SNP), smoking and alcohol consumption with the risk of laryngeal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25510985
DOI: 10.1007/s00405-014-3435-2

Genes

XRCC3

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