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Article

Intermittent cardiac overload results in adaptive hypertrophy and provides protection against left ventricular acute pressure overload insult.

The Journal of physiology - 1 Sept 2015

Moreira-Gonçalves Daniel, Henriques-Coelho Tiago, Fonseca Hélder, Ferreira Rita, Padrão Ana Isabel, Santa Cátia, Vieira Sara, Silva Ana Filipa, Amado Francisco, Leite-Moreira Adelino, Duarte José Alberto

Abstract excerpt

The present study aimed to test whether a chronic intermittent workload could induce an adaptive cardiac phenotype Chronic intermittent workload induced features of adaptive hypertrophy This was paralleled by protection against acute pressure overload insult The heart may adapt favourably to balanced demands, regardless of the nature of the stimuli. The present study aimed to test whether submitting the healthy...

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Identifiers

PMID: 26010517
DOI: 10.1113/JP270685
PMCID: PMC4575575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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