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Article

Lack of galectin-3 up-regulates IgA expression by peritoneal B1 lymphocytes during B cell differentiation.

Cell and tissue research - 1 Feb 2016

Oliveira Felipe L, Bernardes Emerson S, Brand Camila, dos Santos Sofia N, Cabanel Mariana P, Arcanjo Kátia D, Brito José M, Borojevic Radovan, Chammas Roger, El-Cheikh Márcia C

Abstract excerpt

Galectin-3 is a β-galactoside-binding protein with an inhibitory role in B cell differentiation into plasma cells in distinct lymphoid tissues. We use a model of chronic schistosomiasis, a well-characterized experimental disease hallmarked by polyclonal B cell activation, in order to investigate the role of galectin-3 in controlling IgA production through peritoneal B1 cells. Chronically infected,...

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Source

Identifiers

PMID: 26003178
DOI: 10.1007/s00441-015-2203-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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