Article
Limited role of mast cells during infection with the parasitic nematode Litomosoides sigmodontis.
PLoS neglected tropical diseases - 1 Jul 2020
Linnemann Lara Christine, Reitz Martina, Feyerabend Thorsten B, Breloer Minka, Hartmann Wiebke
Abstract excerpt
Mast cells are innate effector cells that due to their localization in the tissue form the first line of defense against parasites. We have previously shown that specifically mucosal mast cells were essential for the termination of the intestinal Strongyloides ratti infection. Here, we analyze the impact of mast cells on the immune response and defense against the tissue-dwelling filarial nematode Litomosoides...
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