Article
Common AZFc structure may possess the optimal spermatogenesis efficiency relative to the rearranged structures mediated by non-allele homologous recombination.
Scientific reports - 22 May 2015
Yang Bo, Ma Yong-yi, Liu Yun-qiang, Li Lei, Yang Dong, Tu Wen-ling, Shen Ying, Dong Qiang, Yang Yuan
Abstract excerpt
The azoopsermia factor c (AZFc) region of human Y-chromosome is an essential genomic segment for spermatogenesis with frequent non-allele homologous recombination (NAHR). Recent case-control studies on the association of the NAHR-based AZFc structural mutations with spermatogenic failure produced inconsistent results. To more precisely evaluate their spermatogenesis effects, we investigated the correlation...
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