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Article

Dynamic nature of the proximal AZFc region of the human Y chromosome: multiple independent deletion and duplication events revealed by microsatellite analysis.

Human mutation - 1 Oct 2008

Balaresque Patricia, Bowden Georgina R, Parkin Emma J, Omran Ghada A, Heyer Evelyne, Quintana-Murci Lluis, Roewer Lutz, Stoneking Mark, Nasidze Ivan, Carvalho-Silva Denise R, Tyler-Smith Chris, de Knijff Peter, Jobling Mark A

Abstract excerpt

The human Y chromosome shows frequent structural variants, some of which are selectively neutral, while others cause impaired fertility due to the loss of spermatogenic genes. The large-scale use of multiple Y-chromosomal microsatellites in forensic and population genetic studies can reveal such variants, through the absence or duplication of specific markers in haplotypes. We describe Y chromosomes in apparently...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18470947
DOI: 10.1002/humu.20757
PMCID: PMC2689608

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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