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Article

Partial duplication at<i>AZFc</i>on the Y chromosome is a risk factor for impaired spermatogenesis in Han Chinese in Taiwan

6 Feb 2007

Abstract excerpt

The Azoospermia Factor c (AZFc) region on the Y chromosome long arm is one of the least stable regions in the human genome. It consists almost entirely of very long repeats and is prone to rearrangement. Numerous structures at AZFc have been identified, and some of them have been reported to be associated with male infertility. We screened 580 Han Chinese in Taiwan for AZFc deletion and duplication using three...

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PMID: 17285591
DOI: 10.1002/humu.20473

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Partial duplication at<i>AZFc</i>on the Y chromosome is a risk factor for impaired spermatogenesis in Han Chinese in TaiwanPMID 17285591Read ↗

Partial AZFc duplications not deletions are associated with male infertility in the Yi population of Yunnan Province, China.Semantic proximity Read ↗

Additional genomic duplications in AZFc underlie the b2/b3 deletion-associated risk of spermatogenic impairment in Han Chinese populationSemantic proximity Read ↗

Gene copy number alterations in the azoospermia-associated AZFc region and their effect on spermatogenic impairmentSemantic proximity Read ↗

Partial deletions are associated with an increased risk of complete deletion in AZFc: a new insight into the role of partial AZFc deletions in male infertilitySemantic proximity Read ↗

The Association of Partial Azoospermia Factor C Deletions and Male Infertility in Northwestern ChinaSemantic proximity Read ↗

Uniform deletion junctions of complete azoospermia factor region c deletion in infertile men in Taiwan.Semantic proximity Read ↗

The b2/b3 subdeletion shows higher risk of spermatogenic failure and higher frequency of complete AZFc deletion than the gr/gr subdeletion in a Chinese population.Semantic proximity Read ↗

Azoospermia factor C subregion of the Y chromosomeSemantic proximity Read ↗

Evolution of the Japanese Y chromosome by analysis of the haplogroups and the deletion of the gene in the AZFc region.Semantic proximity Read ↗

Sequence family variant loss from the AZFc interval of the human Y chromosome, but not gene copy loss, is strongly associated with male infertility.Semantic proximity Read ↗

A frequent Y chromosome b2/b3 subdeletion shows strong association with male infertility in Han-Chinese populationSemantic proximity Read ↗

Microdeletions of a Y-specific marker, Yfm1, and implications for a role in spermatogenesis.Semantic proximity Read ↗

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