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DAZ duplications confer the predisposition of Y chromosome haplogroup K* to non-obstructive azoospermia in Han Chinese populations.

Human reproduction (Oxford, England) - 1 Sept 2013

Lu Chuncheng, Wang Ying, Zhang Feng, Lu Feng, Xu Miaofei, Qin Yufeng, Wu Wei, Li Shilin, Song Ling, Yang Shuping, Wu Di, Jin Li, Shen Hongbing, Sha Jiahao, Xia Yankai, Hu Zhibin, Wang Xinru

Abstract excerpt

STUDY QUESTION: What are the genetic causes for the predisposition of certain Y chromosome haplogroups (Y-hgs) to spermatogenic impairment? SUMMARY ANSWER: The AZFc(azoospermia factor c)/DAZ (deleted in azoospermia) duplications might underlie the susceptibility of Y-hg K* to spermatogenic impairment. WHAT IS KNOWN ALREADY: The roles of Y chromosomal genetic background in spermatogenesis are controversial and...

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PMID: 23696539
DOI: 10.1093/humrep/det234

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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