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Article

Gene copy number alterations in the azoospermia-associated AZFc region and their effect on spermatogenic impairment

16 Jun 2014

Abstract excerpt

The azoospermia factor c (AZFc) region in the long arm of human Y chromosome is characterized by massive palindromes. It harbors eight multi-copy gene families that are expressed exclusively or predominantly in testis. To assess systematically the role of the AZFc region and these eight gene families in spermatogenesis, we conducted a comprehensive molecular analysis (including Y chromosome haplogrouping, AZFc...

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Share to Chromosomal and Genetic Variations
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PMID: 24935076
DOI: 10.1093/molehr/gau043

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Related research

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Gene copy number alterations in the azoospermia-associated AZFc region and their effect on spermatogenic impairmentPMID 24935076Read ↗

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Gene copy number reduction in the azoospermia factor c (AZFc) region and its effect on total motile sperm count.Semantic proximity Read ↗

Partial deletions are associated with an increased risk of complete deletion in AZFc: a new insight into the role of partial AZFc deletions in male infertilitySemantic proximity Read ↗

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