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Article

Effect of N-acetylcysteine in COPD patients with different microsomal epoxide hydrolase genotypes.

International journal of chronic obstructive pulmonary disease - 1 Jan 2015

Zhang Jian-Qing, Zhang Jia-Qiang, Liu Hua, Zhao Zhi-Huan, Fang Li-Zhou, Liu Ling, Fu Wei-Ping, Shu Jing-Kui, Feng Jia-Gang, Dai Lu-Ming

Abstract excerpt

BACKGROUND: The role of the antioxidant N-acetylcysteine (NAC) in the treatment of chronic obstructive pulmonary disease (COPD) has not been clarified as yet. In early studies, we found that the proportion of smokers with COPD having extremely slow/slow microsomal epoxide hydrolase (EPHX1) enzyme activity is significantly higher than that in healthy smokers. The purpose of this study was to evaluate whether...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25999707
DOI: 10.2147/COPD.S79710
PMCID: PMC4437521

Genes

EPHX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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