Article
Generation of intersubtype human immunodeficiency virus type 1 recombinants in env gene in vitro: influences in the biological behavior and in the establishment of productive infections.
Virology - 15 Mar 2000
Costa L J, Munerato P, Diaz R S, Tanuri A
Abstract excerpt
The occurrence of human immunodeficiency virus type 1 (HIV-1) recombinant genomes belonging to different subtypes is a common event in regions where more than two subtypes cocirculate. Although there are accumulating data toward an increase in the number of intersubtype recombinants, little has been addressed about the biological behavior of such mosaic genomes. This work reports the biological characterization...
Topics
- Amino Acid Sequence
- Chimera
- Gene Expression Regulation, Viral
- Genes, env
- HIV Infections
- HIV-1
- HeLa Cells
- Humans
- Leukocytes, Mononuclear
- Molecular Sequence Data
- Phenotype
- Recombination, Genetic
- Transfection
- Tumor Cells, Cultured