Article
Identifying the important HIV-1 recombination breakpoints.
PLoS computational biology - 12 Sept 2008
Archer John, Pinney John W, Fan Jun, Simon-Loriere Etienne, Arts Eric J, Negroni Matteo, Robertson David L
Abstract excerpt
Recombinant HIV-1 genomes contribute significantly to the diversity of variants within the HIV/AIDS pandemic. It is assumed that some of these mosaic genomes may have novel properties that have led to their prevalence, particularly in the case of the circulating recombinant forms (CRFs). In regions of the HIV-1 genome where recombination has a tendency to convey a selective advantage to the virus, we predict that...
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