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Article

Astrocytic β1-integrin affects cellular composition of murine blood brain barrier in the cerebral cortex.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Aug 2015

Venkatesan Charu, Birch Derin, Peng Chian-Yu, Kessler John A

Abstract excerpt

The blood brain barrier (BBB) is composed of endothelial cells, astrocytes, and pericytes and maintains functional homeostasis by regulating transport of ions, fluid and cells between blood and neural tissue. The cellular and molecular pathways that contribute to the formation of the BBB in the developing brain have not been fully deciphered. β1-integrin (β1-itg) within endothelial cells is known to play a...

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Identifiers

PMID: 25997909
DOI: 10.1016/j.ijdevneu.2015.05.005

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GFAP

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