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Article

Glut1/SLC2A1 is crucial for the development of the blood‐brain barrier in vivo

29 Oct 2010

Abstract excerpt

OBJECTIVE: The overall permeability of the blood-brain barrier (BBB) is regulated by specialized cerebral endothelial cells and their junctional complexes, consisting of adherens junctions (AJs) and tight junctions (TJs). Among the members of the glucose transporters (Glut), Glut1 is a unique molecule expressed in the cerebral endothelial cells. Glut1 and the junctional proteins are concomitantly downregulated in...

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PMID: 21194153
DOI: 10.1002/ana.22318

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