Article
Surface invasive cleavage assay on a maskless light-directed diamond DNA microarray for genome-wide human SNP mapping.
The Analyst - 7 Jul 2015
Nie Bei, Yang Min, Fu Weiling, Liang Zhiqing
Abstract excerpt
The surface invasive cleavage assay, because of its innate accuracy and ability for self-signal amplification, provides a potential route for the mapping of hundreds of thousands of human SNP sites. However, its performance on a high density DNA array has not yet been established, due to the unusual "hairpin" probe design on the microarray and the lack of chemical stability of commercially available substrates....
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