Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL

21 May 2015

Abstract excerpt

The thrombopoietic environment of the neonate is established during prenatal life; therefore, a comprehensive understanding of platelet-forming cell development during embryogenesis is critical to understanding the etiology of early-onset thrombocytopenia. The recent discovery that the first platelet-forming cells of the conceptus are not megakaryocytes (MKs) but diploid platelet-forming cells (DPFCs) revealed a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lipid metabolism and disorders
Share to Platelet Disorders and Treatments
Share to Zebrafish Biomedical Research Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25995324
DOI: 10.1182/blood-2014-12-616607

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPLPMID 25995324Read ↗

Megakaryocyte ontogeny: Clinical and molecular significance.Semantic proximity Read ↗

Lung megakaryocytes display distinct transcriptional and phenotypic properties.Semantic proximity Read ↗

NF-E2, FLI1 and RUNX1 collaborate at areas of dynamic chromatin to activate transcription in mature mouse megakaryocytesSemantic proximity Read ↗

The Aorta-Gonad-Mesonephros niche shapes the functions of yolk sac-derived macrophages involved in hematopoietic stem and progenitor cell generation <i>ex vivo</i>Semantic proximity Read ↗

Molecular and Transcriptional Regulation of Megakaryocyte DifferentiationSemantic proximity Read ↗

Induction of hyperproliferative fetal megakaryopoiesis by an N-terminally truncated GATA1 mutant.Semantic proximity Read ↗

Hematopoietic transcription factor mutations: important players in inherited platelet defects.Semantic proximity Read ↗

The genomic and proteomic blueprint of mouse megakaryocytes derived from embryonic stem cells.Semantic proximity Read ↗

Cell-Autonomous Function of Runx1 Transcriptionally Regulates Mouse Megakaryocytic MaturationSemantic proximity Read ↗

Mice Lacking Transcription Factor NF-E2 Provide In Vivo Validation of the Proplatelet Model of Thrombocytopoiesis and Show a Platelet Production Defect That Is Intrinsic to MegakaryocytesSemantic proximity Read ↗

Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/MafSemantic proximity Read ↗

Erythro-myeloid progenitor origin of Hofbauer cells in the early mouse placentaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.