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Article

Analysis of Hereditary Nonpolyposis Colorectal Cancer in Malay Cohorts using Immunohistochemical Screening.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015

Wan Juhari Wan Khairunnisa, Wan Abdul Rahman Wan Faiziah, Mohd Sidek Ahmad Shanwani, Abu Hassan Muhammad Radzi, Ahmad Amin Noordin Khairul Bariah, Zakaria Andee Dzulkarnaen, Macrae Finlay, Zilfalil Bin Alwi

Abstract excerpt

BACKGROUND: Lynch syndrome (LS) is an inherited predisposition to colorectal, endometrial (uterine) and other cancers. Although most cancers are not inherited, about 5 percent (%) of people who have colorectal or endometrial cancer have the Lynch syndrome. It involves the alteration of mismatch repair (MMR) genes; MLH1, MSH2, MSH6 or PMS2. In this study, we analyzed the expression of MMR proteins in colorectal...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

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Share to Mismatch Repair Endonuclease PMS2

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Source

Identifiers

PMID: 25987035
DOI: 10.7314/apjcp.2015.16.9.3767

Genes

MLH1
MSH2
MSH6
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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