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Article

Review article: the Lynch syndrome (hereditary nonpolyposis colorectal cancer)*

1 Dec 2007

Abstract excerpt

BACKGROUND: The most common inherited colorectal cancer syndrome is the Lynch syndrome (HNPCC) which is characterized by the development of colorectal, endometrial, and other cancers and the presence of microsatellite instability (MSI) in tumours. The syndrome is due to a mutation in one of the mismatch repair (MMR) genes: MSH2, MLH1, MSH6 and PMS2. AIMS: To evaluate the clinical features of the Lynch syndrome...

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Identifiers

PMID: 18081655
DOI: 10.1111/j.1365-2036.2007.03479.x

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