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Article

Cancer-risk by family history and mismatch-repair mutation in Lynch syndrome.

Scandinavian journal of gastroenterology - 1 Jun 2020

Marques-de-Sá Inês, Castro Rui, Pita Inês, Dinis-Ribeiro Mário, Brandão Catarina

Abstract excerpt

Introduction: Surveillance of Lynch syndrome (LS) is recommended to reduce cancer-risk. There is an increased awareness that cancer-risk may vary with mismatch-repair mutation and family history. However, gene-specific and family-specific surveillance are not recommended. Therefore, we aimed to estimate the cumulative incidence of lesions and to assess the cancer-risk by family history and mismatch-repair...

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Identifiers

PMID: 32448028
DOI: 10.1080/00365521.2020.1766553

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