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Article

Germline mutation analysis of MLH1 and MSH2 in Malaysian Lynch syndrome patients.

World journal of gastroenterology - 28 Feb 2012

Zahary Mohd Nizam, Kaur Gurjeet, Abu Hassan Muhammad Radzi, Singh Harjinder, Naik Venkatesh R, Ankathil Ravindran

Abstract excerpt

AIM: To investigate the protein expression profile of mismatch repair (MMR) genes in suspected cases of Lynch syndrome and to characterize the associated germline mutations. METHODS: Immunohistochemical analysis of tumor samples was performed to determine the protein expression profile of MMR protein. Germline mutation screening was carried out on peripheral blood samples. The entire exon regions of MLH1 and MSH2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 22371642
DOI: 10.3748/wjg.v18.i8.814
PMCID: PMC3286145

Genes

MLH1
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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