Article
Intakes of omega-3 polyunsaturated fatty acids and blood pressure change over time: Possible interaction with genes involved in 20-HETE and EETs metabolism.
Prostaglandins & other lipid mediators - 1 Jul 2015
Tagetti Angela, Ericson Ulrika, Montagnana Martina, Danese Elisa, Almgren Peter, Nilsson Peter, Engström Gunnar, Hedblad Bo, Minuz Pietro, Orho-Melander Marju, Fava Cristiano, Melander Olle
Abstract excerpt
BACKGROUND: A high intake of omega-3 polyunsaturated fatty acids (ω-3 PUFAs), has been associated with reduced levels of blood pressure (BP). Their antihypertensive action may be due to the reduction of the ω-6/ω-3 ratio and the resulting competitive effect of ω-3 as compared to arachidonic acid (an ω-6 PUFA) as a substrate of cytochrome P450 (CYP450) enzymes involved in the production of vasoactive mediators....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.