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Article

Effect of the PPAR-Alpha L162V polymorphism on the cardiovascular disease risk factor in response to n-3 polyunsaturated fatty acids.

Journal of nutrigenetics and nutrigenomics - 1 Jan 2008

Caron-Dorval Dominique, Paquet Pascale, Paradis Ann-Marie, Rudkowska Iwona, Lemieux Simone, Couture Patrick, Vohl Marie-Claude

Abstract excerpt

BACKGROUND: Dietary n-3 polyunsaturated fatty acids (PUFAs) decrease the risk of cardiovascular disease (CVD). Yet, genetic variations of the gene encoding the peroxisome proliferator-activated receptor-alpha (PPARalpha) can also modulate CVD risk factors. Since fatty acids, including n-3 PUFAs, are natural ligands of PPARalpha, a gene-diet interaction effect could be observed. AIMS: To examine whether n-3 PUFA-...

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Identifiers

PMID: 19776627
DOI: 10.1159/000137555

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effect of the PPAR-Alpha L162V polymorphism on the cardiovascular disease risk factor in response to n-3 polyunsaturated fatty acids.PMID 19776627Read ↗

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