Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of complement in IgA nephropathy

13 Nov 2015

Abstract excerpt

Immunoglobulin A nephropathy (IgAN) is characterized by the deposition of IgA in the mesangium of glomeruli. This mesangial IgA has been found to consist mainly of polymeric IgA1 which drives the activation of the mesangial cells and results in excessive production of several inflammatory mediators. The activation of mesangial cells is amplified by the ability of IgA to activate the complement system, originally...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement system in diseases
Share to Platelet Disorders and Treatments
Share to Renal Diseases and Glomerulopathies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26567162
DOI: 10.1007/s40620-015-0245-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of complement in IgA nephropathyPMID 26567162Read ↗

Targeting complement in IgA nephropathySemantic proximity Read ↗

The complement system in IgAN: mechanistic context for therapeutic opportunitiesSemantic proximity Read ↗

IgA nephropathy: new insights into the role of complementSemantic proximity Read ↗

Current Understanding of the Role of Complement in IgA Nephropathy.Semantic proximity Read ↗

Complement catalyzing glomerular diseasesSemantic proximity Read ↗

Urinary markers of the alternative and lectin complement pathway are increased in IgA vasculitis nephritisSemantic proximity Read ↗

The role of complement in kidney diseaseSemantic proximity Read ↗

Complement-Mediated Glomerular Diseases: A Tale of 3 PathwaysSemantic proximity Read ↗

The complement system in IgA nephropathy and Henoch-Schönlein purpura: functional and genetic aspects.Semantic proximity Read ↗

Challenges in IgA Nephropathy Management: An Era of Complement InhibitionSemantic proximity Read ↗

The role of the alternative pathway of complement activation in glomerular diseases.Semantic proximity Read ↗

Complement-mediated kidney diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.