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Article

The impact of HER2 phenotype of circulating tumor cells in metastatic breast cancer: a retrospective study in 107 patients.

BMC cancer - 14 May 2015

Wallwiener Markus, Hartkopf Andreas Daniel, Riethdorf Sabine, Nees Juliane, Sprick Martin Ronald, Schönfisch Birgitt, Taran Florin-Andrei, Heil Jörg, Sohn Christof, Pantel Klaus, Trumpp Andreas, Schneeweiss Andreas

Abstract excerpt

BACKGROUND: In metastatic breast cancer (MBC), antigen profiles of metastatic tissue and primary tumor differ in up to 20 % of patients. Reassessment of predictive markers, including human epidermal growth factor receptor 2 (HER2) expression, might help to optimize MBC treatment. While tissue sampling is invasive and often difficult to repeat, circulating tumor cell (CTC) analysis requires only a blood sample and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25972110
DOI: 10.1186/s12885-015-1423-6
PMCID: PMC4435916

Genes

MET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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