Therapeutic intervention based on circulating tumor cell phenotype in metastatic breast cancer: concept of the DETECT study program.

doi:10.1007/s00404-015-3879-7

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Therapeutic intervention based on circulating tumor cell phenotype in metastatic breast cancer: concept of the DETECT study program.

Archives of gynecology and obstetrics - 1 Feb 2016

Schramm Amelie, Friedl Thomas W P, Schochter Fabienne, Scholz Christoph, de Gregorio Nikolaus, Huober Jens, Rack Brigitte, Trapp Elisabeth, Alunni-Fabbroni Marianna, Müller Volkmar, Schneeweiss Andreas, Pantel Klaus, Meier-Stiegen Franziska, Hartkopf Andreas, Taran Florin-Andrei, Wallwiener Diethelm, Janni Wolfgang, Fehm Tanja

Abstract excerpt

PURPOSE: The aim of the ongoing DETECT study program is to evaluate therapeutic intervention based on phenotypes of circulating tumor cells (CTC) in patients with metastatic breast cancer (MBC). Currently (as of July 2015) more than half of the projected about 2000 patients with MBC have already been screened for CTC. METHODS: Women with HER2-negative primary tumor and presence of CTC are recruited into different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal, Humanized

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Lapatinib

Share to Neoplastic Cells, Circulating

Share to Quality of Life

Share to Quinazolines

Share to Receptor, ErbB-2

Share to Trastuzumab

Source

Open in PubMed

Identifiers

PMID: 26354331
DOI: 10.1007/s00404-015-3879-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Therapeutic intervention based on circulating tumor cell phenotype in metastatic breast cancer: concept of the DETECT study program.PMID 26354331Read ↗

The impact of HER2 phenotype of circulating tumor cells in metastatic breast cancer: a retrospective study in 107 patients.Semantic proximity Read ↗

Circulating tumor cells in breast cancer beyond the genotype of primary tumor for tailored therapy.Semantic proximity Read ↗

Circulating Tumor Cells (CTCs) Heterogeneity in Metastatic Breast Cancer: Different Approaches for Different Needs.Semantic proximity Read ↗

Circulating tumor cells in breast cancer: functional heterogeneity, pathogenetic and clinical aspects.Semantic proximity Read ↗

A Comprehensive Molecular Analysis of in Vivo Isolated EpCAM-Positive Circulating Tumor Cells in Breast CancerSemantic proximity Read ↗

Early Evaluation of Risk Stratification and Clinical Outcomes for Patients with Advanced Breast Cancer through Combined Monitoring of Baseline Circulating Tumor Cells and DNA.Semantic proximity Read ↗

Incorporating MicroRNA into Molecular Phenotypes of Circulating Tumor Cells Enhances the Prognostic Accuracy for Patients with Metastatic Breast CancerSemantic proximity Read ↗

Minimal residual disease in breast cancer and gynecological malignancies: phenotype and clinical relevance.Semantic proximity Read ↗

Heterogeneity of Circulating Tumor Cells in Breast Cancer: Identifying Metastatic Seeds.Semantic proximity Read ↗

The influence of removal of primary tumor on incidence and phenotype of circulating tumor cells in primary breast cancer.Semantic proximity Read ↗

Circulating tumor cell phenotype detection based on epithelial-mesenchymal transition markers combined with clinicopathological risk has potential to better predict recurrence in stage III breast cancer treated with neoadjuvant chemotherapy: a pilot study.Semantic proximity Read ↗

Detection and Characterization of Circulating Tumor Associated Cells in Metastatic Breast Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.