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Article

How I treat T-cell acute lymphoblastic leukemia in adults.

Blood - 13 Aug 2015

Litzow Mark R, Ferrando Adolfo A

Abstract excerpt

T-cell immunophenotype of acute lymphoblastic leukemia (T-ALL) is an uncommon aggressive leukemia that can present with leukemic and/or lymphomatous manifestations. Molecular studies are enhancing our understanding of the pathogenesis of T-ALL, and the discovery of activating mutations of NOTCH1 and FBXW7 in a majority of patients has been a seminal observation. The use of pediatric intensive combination...

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Identifiers

PMID: 25966987
DOI: 10.1182/blood-2014-10-551895

Genes

NOTCH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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