Article
Biology and Treatment Paradigms in T Cell Acute Lymphoblastic Leukemia in Older Adolescents and Adults.
Current treatment options in oncology - 28 May 2020
Patel Anand A, Thomas Joseph, Rojek Alexandra E, Stock Wendy
Abstract excerpt
OPINION STATEMENT: T cell acute lymphoblastic leukemia (T-ALL) occurs in approximately 25-30% of adult ALL diagnoses. Historically, B cell ALL (B-ALL) and T-ALL have been treated in the same fashion despite differences in the biology of disease. Outcomes in the adolescent/young adult (AYA) population have improved significantly with the utilization of pediatric-based regimens. In addition, there may now be a role...
Topics
- Adolescent
- Adult
- Age Factors
- Biomarkers, Tumor
- Clinical Decision-Making
- Combined Modality Therapy
- Disease Management
- Disease Susceptibility
- Drug Resistance
- Genetic Predisposition to Disease
- Humans
- Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
- Recurrence
- Retreatment
- Treatment Outcome
- Young Adult